Bioinformatician - Single-cell Analysis

Salary range:

£32,578 - £39,938

Post No.


Contract length:

36 months



Opening date:

16 November 2021

Closing date:

13 December 2021

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Bioinformatician - Single-cell Analysis

Applications are invited for a Bioinformatician to join the Laboratory of Dr Iain Macaulay and Dr Wilfried Haerty in the Engineering Biology Programme at the Earlham Institute, based in Norwich, UK.


The Macaulay and Haerty groups focus on experimental and computational method development for single-cell genomics. The role will also work closely with the group of Dr David Monk at UEA, who works on the epigenetics of the placenta. The three groups are working closely on this project to develop new approaches to understand the unique regulatory landscape of placental cells.

The role:

The successful candidate will join this exciting collaborative project, which will explore epigenetic and transcriptomic diversity in the placenta, with the aim of identifying the mechanisms regulating placenta-specific imprinted gene expression. They will analyse and integrate single-cell and cell-type specific epigenomic (DNA methylation, CUT&TAG, capture Hi-C), transcriptomic data (scRNA and low-input RNAseq) and multi-omic data (scM&T-seq) to produce a unique epigenetic and transcriptomic landscape of placental development.

The post will be based at EI but will but will be part of a close collaboration between the three research groups. The successful candidate will work with members of each group on a regular basis and will be involved in the complete lifespan of the experiments, from design through to publication.

The ideal candidate:

The ideal candidate will have a PhD in bioinformatics, computational genomics or a related subject. They will have demonstrable experience working with genomic/epigenomic/transcriptomic data, and experience with single-cell genomics analysis. The candidate should have a demonstrable expertise in programming with Python or R.

Additional information:

Salary on appointment will be within the range £32,578 to £39,938 per annum depending on qualifications and experience. This is a full time post for a contract of 36 months.

For further information and details of how to apply, visit the application page by clicking 'Apply' above, or contact the Human Resources team on 01603 450462 or quoting reference 1004141.

As a Disability Confident employer, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy.

The closing date for applications will be 13th December 2021.

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