Postdoctoral Research Scientist (Metagenome Bioinformatics)

Salary range:

£32,255 - £39,345

Post No.


Contract length:

36 Months

Opening date:

04 February 2021

Closing date:

28 February 2021

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Applications are invited for a Postdoctoral Research Scientist to join the Laboratory of Dr Quince in the Organisms and Ecosystems Programme at the Earlham Institute, based in Norwich, UK.


The Quince group focusses on both theoretical and experimental methods for microbial community analysis. Combining statistical bioinformatics with technological developments in sequencing and ‘omics data generation to address problems such as metagenome strain resolution and trait inference. These methods are applied to both simple bench top experiments with microbial communities and large scale 'omics studies. These studies span a range of environments from host associated to biotechnology applications.

The role:

We are looking for an individual with a high-level of quantitative skills to join a project resolving strain genomes from metagenomes. The study of microbiomes has revolutionised our understanding of the microbial world but tools capable of extracting individual genomes from complex communities are still lacking. Methods for genome binning can use shared features of contigs from metagenome assemblies to generate species bins but these will be composites of multiple closely related organisms. Instead, we will develop methods that work directly on assembly graphs, exploit a combination of novel sequencing technologies, correlations in time series, and recent algorithmic developments to resolve genomes to the strain level.

The ideal candidate:

The ideal candidate would combine a knowledge of metagenomics assembly, Bayesian statistics and software development but excellence in any of these areas would be sufficient. You will have a PhD in bioinformatics or statistics or related subject area with a strong element of statistical modelling. Knowledge of software programming in at least one language e.g. R, Python, C/C++ is essential.

Additional information:

Salary on appointment will be within the range £32,255 to £39,345 per annum depending on qualifications and experience. This is a full-time post for a contract of 3 years.

For further information and details of how to apply, please visit our web site or contact the Human Resources team on 01603 450462 or quoting reference 1003980.

As a Disability Confident employer, we guarantee to offer an interview to all disabled applicants who meet the essential criteria for this vacancy.

The closing date for applications will be 28 February 2021.