I have an academic background in Microbial Computational Systems Biology mostly focussed on the reconstruction of bacterial regulatory networks and integration of heterogeneous datasets.
My current research interests revolve around using various bioinformatics methods and approaches to study the molecular cross-talk between bacteria and humans in the gut environment particularly in the context of autophagy, immunomodulation, and homeostasis as well as in disease states such as Ulcerative Colitis and Crohns Disease.
The proteome of extracellular vesicles produced by the human gut bacteria Bacteroides thetaiotaomicron in vivo is influenced by environmental and host-derived factorsThe proteome of extracellular vesicles produced by the human gut bacteria Bacteroides ...
A systems genomics approach to uncover patient-specific pathogenic pathways and proteins in ulcerative colitis.
Extracellular vesicles produced by the human commensal gutbacteriumBacteroides thetaiotaomicronaffect host immunepathways in a cell-type specific manner that are altered ininflammatory bowel disease
Multi-layered networks of SalmoNet2 enable strain comparisons of the Salmonella genus on a molecular level
SignaLink3: a multi-layered resource to uncover tissue-specific signaling networks.
Computational Biology and Machine Learning Approaches to Understand Mechanistic Microbiome-Host Interactions
ViralLink: An integrated workflow to investigate the effect of SARS-CoV-2 on intracellular signalling and regulatory pathways
Evolution of regulatory networks associated with traits under selection in cichlids.
Extracellular vesicles released by the human gut symbiont Bacteroides thetaiotaomicron in the mouse intestine are enriched in a selected range of proteins that influence host cell physiology and metabolism
ULK1 and ULK2 are less redundant than previously thought: computational analysis uncovers distinct regulation and functions of these autophagy induction proteins.
MicrobioLink: An Integrated Computational Pipeline to Infer Functional Effects of Microbiome-Host Interactions.
Big data in IBD: big progress for clinical practice.
“Autophagy is the process by which cytoplasmic components are engulfed in double-membraned vesicles before being delivered to the lysosome to be degraded. Defective autophagy has been linked to a vast array of human pathologies. The molecular mechani...
Regulatory network analysis of Paneth cell and goblet cell enriched gut organoids using transcriptomics approaches.
- Recipient of the Scholarship for oustanding students with excellent academic performance by the Technical University Hamburg Harburg and Hanseatic Hamburg, Germany.
- Awarded with the ”HypovereinsBank” scholarship for carrying out the MBA program at the Northern Institute of Technology Management, Hamburg, Germany.
- 25th Rank Holder during Bachelor studies (in the Industrial Biotechnology stream) conducted by Anna University, India.