My project is a subproject of a more extensive research funded by the CRUK Accelerator Award. This project is a collaboration between institutes in Italy and the United Kingdom. The goal of this partnership is to deliver tools that will bring single-cell multiomics analyses towards clinical applications.
In my project, I will apply single-cell genome and transcriptome sequencing to reconstruct clonal evolution in patient-derived organoids established from human colorectal cancer (CRC) samples. In addition, I will integrate genomic and transcriptomic datasets from the same cells to infer CRC evolution in the presence and absence of drug treatments.
During my BSc (Hons) degree in Biomedical Science (University of Essex), I undertook a placement year working as a trainee biomedical scientist. After graduating from my MSc in Biomedical Sciences at the University of Brighton, I worked as a research technician for AstraZeneca, where I leant about the drug development process. I realized how much progress had been made in cancer research and how much more there is yet to do. My research interest lies in translational science, as I hope to carry out meaningful research that may one day help those who need it most.