• Research

Iain Macaulay

Technical Development Group Leader

Biography.

Contact details:

  • +44 (0) 1603 450 595 

iain.macaulay@earlham.ac.uk 

@whatchamacaulay 

Dr Iain Macaulay is a Group Leader in Technical Development at the Earlham Institute. The Group’s research focus is on the development and application of new approaches for integrated sequencing or “multi-omics” of single cells and low-input genome samples. Such tools allow genetic, epigenetic and transcriptional heterogeneity in diverse biological systems – including bacteria, plants, and animals – to be investigated at cellular resolution. 

 

Publications.

G&T-seq: parallel sequencing of single-cell genomes and transcriptomes. 

Macaulay IC, Haerty W, Kumar P, Li YI, Hu TX, Teng MJ, Goolam M, Saurat N, Coupland P, Shirley LM, Smith M, Van der Aa N, Banerjee R, Ellis PD, Quail MA, Swerdlow HP, Zernicka-Goetz M, Livesey FJ, Ponting CP, Voet T. 

Nat Methods. 2015 Jun;12(6):519-22. doi: 10.1038/nmeth.3370. Epub 2015 Apr 27. 

Single cell genomics: advances and future perspectives. 

Macaulay IC, Voet T. PLoS Genet. 2014 Jan 30;10(1):e1004126. doi: 10.1371/journal.pgen.1004126. 

Related reading.