Year in industry.

Earlham’s Year in Industry programme offers two placements per academic year, and each of these provide different routes for students based on preferred skills development and academic requirements of the student’s university*.

One placement is within our Genomics Pipelines group, where the student will predominantly be based in the laboratory, gaining an understanding of next-generation sequencing workflows, as well as spending time learning about downstream computational analysis of the data. The student will be focussing on developing innovative methods to address a specific biological question, including experimental design, protocol optimisation, and data analysis.

The other placement will sit within one of our research faculty groups. This placement will likely predominantly focus on computational methods of data analysis, however, dependent upon the selection of projects available at placement commencement, there may be a laboratory-based component allowing the student to follow the project from sample receipt, through preparation, sequencing, analysis and interpretation.

Our students spend the first few weeks at EI working in parallel, getting to know everyone and everything from project design and scheduling, to generating libraries and loading sequencing platforms, to downstream bioinformatic analysis, including assembly and annotation. This way, students are exposed to the organisational structure, how different groups interact and, most importantly, get to know everyone along to way to feel truly embedded within the institute.

Following completion of the initial weeks at the institute, the students then follow their chosen placement path either within Genomics Pipelines, or within one of the research faculty groups*.

*It is the student’s responsibility to ensure that the placement type applied for meets the academic requirements criteria as set out in their university’s handbook.

Applications for 2018/2019 academic year are now open.

Applications close Sunday 1 April 2018.

For more information contact Dr Emily Angiolini at yii@earlham.ac.uk.

Emily Angiolini

Emily Angiolini
Scientific Training and Education Team Manager

Example Project.

Understanding microbe-host autophagy interactions using system and network biology approaches.

Tamás Korcsmáros and Padhmanand Sudhakar

Background
Systems biology has revolutionised our way of thinking about biological systems. Network representation has furthered our understanding of how various cellular processes co-ordinate with each other to bring about homeostasis and to a greater extent about how changes in cellular processes can lead to complex diseases, such as inflammatory bowel disease (IBD) and cancer.

Autophagy (self-eating), an important cellular process which degrades unwanted cellular compartments is regulated by molecular networks. Interestingly, autophagy not only degrades host molecules but also intracellular pathogens. Conversely, autophagy is often manipulated by various intracellular pathogens, such as Salmonella. On the other hand, autophagy being a fundamental process is involved in maintaining homeostasis in the gut by participating in various host immunomodulatory pathways elicited upon exposure to the gut microbial community including many commensal and probiotic bacteria. In our group, one of the core research areas we are focussing on is the systems-level modulation of autophagy by various intracellular pathogens and extracellular commensal/probiotic bacterial species.

Aim
In this project, the student will examine the effect of specific pathogens such as Salmonella and specific probiotics such as Bifidobacterium and other novel commensals on the host signalling network, especially on those pathways that control autophagy in the gut.

Eligibility.

Open to UK undergraduate students only You must be a enrolled in a degree with a year in industry degree programme or degree program that offers an optional year out, currently not studying in either your first or final year, and studying one of the following disciplines:

  • Biological sciences
  • Natural sciences
  • Biochemistry
  • Computer science
  • Mathematics
  • Physics

How it works.

  • Applications Open 1 March 2018 and close 1 April 2018
  • Interviews will be w/c 23rd April 2018
  • Contracts finalised in July
  • Placements commence mid-September with rotation
  • Students split into Genomic Pipelines and Research Faculty mid-October
  • Presentation to EI staff at end of placement
  • Report on progress
  • 12 months post placement feedback
  • 5 years post placement feedback

Apply.

To apply for a Year in Industry placement for the academic year 2018/19, please send the following to yii@earlham.ac.uk :

  • An up-to-date CV, including but not limited to: educational history and results, work experience and transferable skills, awards, contact details of at least 2 referees
  • A covering letter, detailing specifically why you want to undertake a placement at Earlham Institute and what you hope to gain from such a placement
  • Please confirm whether you wish to apply to one or other, or both of the Genomics Pipelines or Research Faculty placements*

*It is the student’s responsibility to ensure that the placement type applied for meets the academic requirements criteria as set out in their university’s handbook.

Year in industry - apply