Alternative splicing in health and disease
Using long-read DNA sequencing we can reveal the many, long-undiscovered forms that a single gene can take - leading us to new therapeutic targets.
Biography
I am a Long-reads TRanscriptome European Consortium (LongTREC) PhD student working with Wilfried Haerty’s and Iain Macaulay’s groups.
LongTREC is a Doctoral Network of the Marie Sklodowska-Curie action program (MSCA-DN) that will develop methods and tools for the analysis of transcriptomic data obtained with the most recent single-molecule, long-reads sequencing technologies.
Before joining EI, I completed my bachelor’s degree in biotechnology at University of Almería (Spain) in 2020, where I had the opportunity to have two international exchanges for five months each: one at Chonnam National University (South Korea) and a second one at Edgewood College (United States). After finishing it, I completed a master’s degree in molecular biology applied to biotechnology business at University of Granada (Spain) in 2021 and a master’s degree in omics data analysis and systems biology at University of Seville (Spain) in 2022.
As part of LongTREC, my PhD project will focus on the study and characterization of alternative splicing regulation in the human immune repertoire at single cells using long-read sequencing technologies (PacBio and ONT) and developing new protocols for low-input material library preparation. In the future, my goal is to use these arising technologies to develop new applications inside the biomedical and the synbio fields.