Research projects

Our projects span the breadth of life sciences, as well as technology development, data infrastructure and knowledge exchange. We have a focus on genomics and bioinformatics, applied to plants, animals and microbes

Our strategy

Air-seq: using DNA sequencing to provide early warning of airborne pathogens

Highly sensitive, real-time, in-field detection of airborne pathogens

Alternative splicing in health and disease

Using long-read DNA sequencing we can reveal the many, long-undiscovered forms that a single gene can take - leading us to new therapeutic targets.

Ash Dieback - the genome, invasion and evolution of the pathogen

What does the genome of the ash dieback pathogen tell us about successful invaders?

Automated DNA Assembly

We are working to push the limits of the size and scale of DNA assembly and have recently automated the fabrication of large DNA assemblies in sub-microliter volumes at the Earlham Biofoundry.

Circadian rhythms in plants

Applying imaging techniques, transcriptomics and machine learning to explore circadian rhythms in a range of plant systems

Collaborative OPen Omics (COPO)

COPO is a data brokering portal for plant scientists to describe, store and retrieve data more easily, using community standards and public repositories that enable the open sharing of results.

Darwin Tree of Life Project

Sequencing the genome of every eukaryote species in the British and Irish Isles

DNA replication and genome evolution and stability.

Single molecule analysis of genome replication

Earth Biogenome Project

A global partnership to sequence the genomes of all lifeforms so we can better understand and harness biodiversity

ELIXIR-UK

Coordinating bioinformatics data, tools, standards and training in the UK, for Europe and beyond.

GastroPak: Understanding and preventing the spread of non-viral gastroenteritis in Pakistan.

Bringing together an international and multidisciplinary team to study the scientific, structural, and cultural factors that drive the spread of non-viral gastroenteritis.

Genetic diversity in wheat

Using natural diversity to identify new markers or genes for key agricultural traits