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Norwich Single-Cell Symposium 2021

Now in its fifth year, the annual Norwich Single-Cell Symposium at Earlham Institute covers single-cell genomics technologies and their application in microbial, plant, animal and human health and disease.

Start date:

14 September 2021

End date:

16 September 2021


10.00am - 3.00pm


Virtual (via Zoom)


Registration deadline:

13 September 2021



About the event.

Single-cell genomic technologies continue to develop at pace, generating new insights into cellular diversity within living systems. This event aims to bring together researchers applying single-cell technologies across a wide range of species.

The symposium covers single-cell genomics technologies and their application in microbial, plant, animal and human health and disease. Offering a forum for researchers to discuss the latest developments in single-cell genomics, whilst networking with other researchers with the intention of catalysing future development and application of single-cell genomics across the UK.

The event will feature talks from invited speakers and selected abstracts, and we are keen to capture as broad a range of single-cell applications as possible. Topics to be covered include:

  • Single-cell genomics in plant and microbial research
  • Single-cell genomics in health, disease and development
  • Single-cell informatics
  • Single-cell technology development


We are offering the opportunity to present your research at the symposium as a short talk, and abstracts should be submitted when you register. We would particularly like to encourage PhD students and early career researchers to submit abstracts, we have reserved plenty of time and space in the schedule to hear from you all!

  • The submission deadline for abstracts is Tuesday 31 August 2021
  • All abstracts must be submitted electronically as part of your registration. Submissions via email will not be accepted
  • Abstract limits are 250 words (excluding title, authors and affiliations)
  • Presenting author should be highlighted in bold
  • Abstracts will be reviewed one a rolling basis, and you will be informed of the outcome within 2 weeks of submitting


Day 1 - Tuesday 14 September 2021

09.45 - 10.00Registrant joining
10.00 - 10.15

Welcome and Introduction to the Norwich Single-Cell Symposium 2021

Iain Macaulay, Earlham Institute

10.15 - 10.45

scDNA-sequencing identifies risk-associated evolutionary trajectories in childhood medulloblastoma development

Marina Danilenko, Newcastle University

10.45 - 11.15

Sequencing uncultured single-celled eukaryotes for the Darwin Tree of Life Project

Jamie McGowan, Earlham Institute

11.15 - 11.45

cellenONE: a platform for miniaturizing workflows and advancing single cell analyses, introduction to cellenCHIP and proteoCHIP

Madeleine Cleal, Cellenion

11.45 - 13.00Lunch break
13.00 - 14.30

Talks from selected speakers

Single-nucleus multi-omics for the study of ageing and dementia in human brain

Melissa Salazar, UCL - UK DRI

FocuSCOPE: A single cell, multi-omics solution to simultaneously analyze tumor variants and microenvironment

Yasaman Arjmand Abbassi, Singleron Biotechnologies

Single cell sequencing for in vitro evolution studies

Matt Bawn, Earlham Institute

SNV discovery from individual scRNA-seq alignments

Anelia Hovarth, George Washington University

14.30 - 15.00

Using single cell omics for target discovery in myeloproliferative neoplasms

Bethan Psaila, MRC Weatherall Institute of Molecular Medicine, University of Oxford

Day 2 - Wednesday 15 September 2021

09.45 - 10.00

Registrants joining

Welcome and Introduction to Day 2

Iain Macaulay, Earlham Institute

10.00 - 10.45

Mapping the temporal and spatial dynamics of the human endometrium

Roser Vento-Tormo, Wellcome Sanger Institute

10.45 - 11.15

Multi-omics analysis of dementia at single cell level

Carlo Sala Frigerio, UK Dementia Research Institute

11.15 - 11.45

Resolving complex biology with ultra-high parameter, single cell multiomic phenotyping

Stephen Hague, 10x Genomics

11.45 - 13.00

Lunch break

13.00 - 14.30

Talks from selected speakers

Clonal heterogeneity in anucleated cells unravelled using RNA barcoding

Edyta Wojtowicz, Earlham Institute

Integrated single-cell genomics of human B cell maturation dynamics

Hamish King, Queen Mary University of London

Bioinformatic Analysis of CD45+ Peritoneal Fluid Cells from Mice Induced with Endometriosis

Yasmin Henlon, University of Warwick

Characterising the embryonic origin of hematoendothelial progenitors, their trajectories and lineage decisions at single cell resolution

Gi Fay Mok, University of East Anglia

14.30 - 15.00

Droplet-based integrative analysis of genome and epigenome of thousands of cells

Davide Cittaro, IRCCS Osperdale San Raffaele

Day 3 - Thursday 16 September 2021

09.45 - 10.00

Registrants joining

Welcome and Introduction to Day 3

Iain Macaulay, Earlham Institute

10.00 - 10.30

Flexible and cost-effective workflows for sensitive full-length single cell RNA-seq

Klaus Hentrich, Cytena


Spatially resolved single-cell genomic analyses of intratumor heterogeneity

Ning Zhang, Karolinska Institutet, SciLifeLab

11.00 - 11.30

Microfluidics for precision single-cell analysis

Jonathan West, University of Southampton

11.30 - 12.00

Full length cDNA concatenation for higher throughput PacBio single cell Iso-Seq

Anita Scoones, PacBio/Earlham Institute

12.00 - 12.15

Close of Event and Feedback

Additional speakers will be added as event details and programme are confirmed.

Further information.

Please carefully review our standard online event booking terms and conditions prior to registering for this event. Completing an online registration and associated payment process will mean that you are bound by these terms and conditions. Any supplemental terms or changes to these conditions on a per event basis will be included on this page. If you have any queries regarding our events or in relation to your booking, please contact us at training@earlham.ac.uk