• Research

Seanna McTaggart

Programme Manager - Darwin Tree of Life

Biography.

Seanna McTaggart provides project management to Earlham Institute’s research initiatives falling within the Earth BioGenome Project remit, including the Wellcome Trust funded Darwin Tree of Life project and a BBSRC strategic fund.

Seanna completed her PhD as a bench scientist studying molecular evolution at the University of Guelph, Canada. She moved to the University of Edinburgh, Department of Zoology, to study innate immune system evolution in the aquatic model organism Daphnia using population genetic/genomic approaches. During her time at Edinburgh University, she held a NERC funded postdoctoral fellowship, a Wellcome Trust junior fellowship and was a Co-investigator on a NERC grant. During these roles, bioinformatic analyses played an increasingly important role in Seanna’s work.

Prior to joining the Earlham Institute, Seanna worked as the Bioinformatics team leader at the Centre for Diagnostics Development, LifeArc, a research charity. At LifeArc, Seanna was trained in project management and working within a quality system, whilst helping to develop diagnostics in disease areas such as breast cancer, neonatal sepsis, inflammatory bowel disease and tuberculosis.

Publications.

Mitogenome phylogeographic analysis of a planktonic crustacean

Fields PD, Obbard DJ, McTaggart SJ, Galimov Y, Little TJ, Ebert D (2018) Molecular Phylogenetics and Evolution 129:138-148

Novel insights into the insect trancriptome response to a natural DNA virus

McTaggart SJ, Hannah T, Bridgett S, Garbutt JS, Kaur G, Boots M (2015) BMC Genomics 16(310)

Transcriptome profiling during a natural host-parasite interaction

McTaggart SJ, Cézard T, Garbutt JS, Wilson PJ, Little TJ (2015) BMC Genomics 16(643)

The development of pathogen resistance in Daphnia magna: implications for disease spread in age-structured populations

Garbutt JS, O'Donoghue AJP, McTaggart SJ, Wilson PJ, Little TJ (2014) Journal of Experimental Biology 217:3929-3934

Daphnia magna shows reduced infection upon secondary exposure to a pathogen

McTaggart SJ, Wilson PJ, Little TJ (2012) Biology Letters 8(6):972-975

Immune genes undergo more adaptive evolution than non-immune system genes in Daphnia pulex

McTaggart SJ, Obbard DJ, Conlon C, Little TJ (2012) BMC Evolutionary Biology 12(63)

The components of the Daphnia pulex immune system as revealed by complete genome sequencing

McTaggart SJ, Conlon C, Colbourne JK, Blaxter ML, Little TJ (2009) BMC Genomics 10(175)

Length Variation in 18S rRNA Expansion Segment 43/e4 of Daphnia obtusa: Ancient or Recurring Polymorphism?

McTaggart SJ, Crease TJ (2009) Journal of Molecular Evolution 69(142)

Nucleotide Polymorphism and Within-Gene Recombination in Daphnia magna and D. pulex, Two Cyclical Parthenogens

Haag CR, McTaggart SJ, Didier A, Little TJ, Charlesworth D (2009) GENETICS 182(1):313-323

An ancient immunity gene duplication in Daphnia magna: RNA expression and sequence analysis of two nitric oxide synthase genes

Labbé P, McTaggart SJ, Little TJ (2009) Developmental & Comparitive Immunology 33(9):1000-1010

The Dscam Homologue of the Crustacean Daphnia Is Diversified by Alternative Splicing Like in Insects

Brites D, McTaggart SJ, Morris K, Anderson J, Thomas K, Colson I, Fabbro T, Little T, Ebert D, Du Pasquier L (2008) Molecular Biology and Evolution 25(7):1429-1439

Rates of Recombination in the Ribosomal DNA of Apomictically Propagated Daphnia obtusa Lines

McTaggart SJ, Dudycha JL, Omilian A, Crease TJ (2007) GENETICS 175(1):311-320

Selection on the Structural Stability of a Ribosomal RNA Expansion Segment in Daphnia obtusa

McTaggart SJ, Crease TJ (2005) Molecular Biology and Evolution 22(5):1309-1319

Related reading.