Biography.
Jose A. Carrasco Lopez is the manager of the Earlham DNA Foundry. The Foundry provides the UK bioscience community access to automated platforms for nano-scale modular DNA assembly, verification and delivery to plant and microbial cells. It is also able to serve as a repository for large collections of DNA parts.
Jose is a microbiologist and molecular biologist interested in pursuing biotech innovation and new approaches to solve human problems.
Jose obtained his PhD in Cellular and Molecular Biology studying the interaction of rhizosphere’s bacteria and legumes as a new tool for heavy metal bioremediation. In post-doctoral research at University of Maryland, Baltimore, USA, he first studied (at Patrik Bavoil lab) the role of the pmp gene family in Chlamydia trachomatis pathogenesis and, later on (at James Galen lab, CVD), developed attenuated Salmonella enterica serovars as live vector vaccine strains.
His experience includes more than 15 years working in the Microbiology, Molecular Biology and Biotechnology fields, studying host/pathogen interactions, human pathogens, developing vaccines and working with bacteria of industrial interest.
Projects.
Publications.
A Bivalent Typhoid Live Vector Vaccine Expressing both Chromosome- and Plasmid-Encoded Yersinia pestis Antigens Fully Protects against Murine Lethal Pulmonary Plague Infection
James E. Galena, Jin Yuan Wanga, Jose A. Carrascoa, Scott A. Lloyda, Gabriela Mellado-Sancheza, Jovita Diaz-McNaira, Olga Francoa, Amanda D. Buskirka, James P. Nataroa and Marcela F. Pasettia
Fierce Competition between Toxoplasma and Chlamydia for Host Cell Structures in Dually Infected Cells
Julia D. Romano, Catherine de Beaumont, Jose A. Carrasco, Karen Ehrenman, Patrik M. Bavoil and Isabelle Coppens
A novel co-infection model with Toxoplasma and Chlamydia trachomatis highlights the importance of host cell manipulation for nutrient scavenging
Julia D. Romano, Catherine de Beaumont, Jose A. Carrasco, Karen Ehrenman, Patrik M. Bavoil and Isabelle Coppens
Altered developmental expression of polymorphic membrane proteins in penicillin-stressed Chlamydia trachomatis
Jose A. Carrasco, Chun Tan, Roger G. Rank, Ru-ching Hsia, and Patrik M. Bavoil
Comparison of koala LPCoLN and human strains of Chlamydia pneumoniae highlights extended genetic diversity in the species
Candice M Mitchell, Kelley M Hovis, Patrik M Bavoil, Garry SA Myers, Jose A Carrasco and Peter Timms
