Developing new methods and tools for real-time metagenomics
The Technology Algorithms Group is focussed on developing computational methods to enhance new sequencing technologies, particularly in the area of real-time and in-field metagenomics and surveillance.
Much of our current projects are focussed on nanopore sequencing, but we are also interested in new applications of short read technologies and other long-read technologies.
Our work usually involves software engineering, data science, algorithm development and data analysis, but members of the group are also active in the wet lab, developing DNA extraction protocols and carrying out sequencing.
Some of our current projects include:
MARTi - MARTi is a software package designed for performing real-time analysis of metagenomic samples using nanopore sequencing.
ALVIS - Alvis is a tool that can generate visualisations for a number of common long read/contig alignment analysis tasks.
NextClip - A tool for comprehensive quality analysis and read preparation for Nextera long mate pair (LMP) libraries.
NanoOK - A tool for comprehensive analysis of Oxford Nanopore MinION sequence data.
MetaCortex - A short-read metagenomic assembler.
Kontaminant - Kmer-based screening of sequencing data.
Bubbleparse - Identification of SNPs from sequencing data without a reference.