This workshop is targeted at early career researchers that want to learn about the latest cutting edge resources available in polyploid wheat.

Food security is recognised as a major global challenge, how to feed the world’s growing population against the backdrop of climate change. With the advent of the era of genomics-based technologies now is the time to translate fundamental plant biology research into crops. This workshop introduces the latest resources and the practical steps you can take to use them in your research.

Trainers

Dr Matthew Clark (EI), Dr Cristobal Uauy (JIC), Dr Ksenia Krasileva (EI), Prof Anthony Hall (EI), Dr Andy Phillips (RRes), Dr Dan Bolser(EBI) and Dr Guy Naamati (EBI).

For the first time, Norwich, UK will host two distinguished conferences - Genome 10K 2017; the biannual conference exploring critical topics essential for understanding how complex animal life evolved through changes in DNA and how we can use this to help save dying species; and Genome Science 2017 - an annual meeting exploring advances in genomics technology and computational methodologies as well as innovation in its application.

The growing Genome 10K Community of Scientists (G10KCOS), made up of leading scientists representing major zoos, museums, research centers, and universities around the world, is dedicated to coordinating efforts in a major tissue specimen collection that will lay the groundwork for a large-scale sequencing and analysis project.

The mission of the Genome 10K COS is to assemble a genomic zoo of some 10,000 vertebrate species to help to understand how complex animal life evolved through changes in DNA and use this knowledge to become better stewards of the planet.

The Genome 10K Project was founded by David Haussler, Oliver Ryder, and Stephen O'Brien, who launched the project in April 2009 at a three-day meeting at the University of California, Santa Cruz.

The Genome Science meeting started out life in 2011 as the UK Next Generation Sequencing meeting, hosted by the DeepSeq facility at the University of Nottingham. Since then it has evolved and grown to be a successful event attracting in the region of 250 delegates each year. This meeting represents a fantastic opportunity for both academia and industry to engage, sharing advances, innovations and challenges in working with -omics data.

In addition to a programme packed full of interesting sessions, we have some fantastic invited speakers who will epitomise the prestige and strength of these conferences. There will also be plenty of networking opportunities, such as the social mixer and conference dinner, as well as the poster sessions. We believe training is crucial to the success of all research projects, including the G10K project and its long-term attainment of objectives. Alongside training for early career researchers we will also include parallel Special Interest Group sessions, which will monitor progress in the sector and set new milestones of the G10K project.

To familiarise students with the molecular and analytical aspects of the genetic screening method Genotype-By-Sequencing (GBS).  

GBS involves the use of short-read sequence data produced from Reduced Representation Libraries (RRL), such as Restricted Site Associated DNA (RAD-tags). GBS libraries can provide a dense set of single nucleotide polymorphisms.

SNP markers are spread evenly across a genome. These markers are useful for a variety of genetic and genomic analyses in both model and non-model organisms. Students will gain experience with the computational pipeline 'Stacks' which was designed for the analysis of such data.

The course will focus on the necessary UNIX skills to handle GBS data, as well as how to clean and demultiplex Illumina sequences. Students will then analyse RAD-seq data de novo to perform a population analysis without the aid of a reference genome using Stacks and structure, and from an organism with a reference genome to generate Fst measures and identify signatures of selection.

Course Prerequisites

Those accepted will be in the planning stages, or producing a Genotype-By-Sequencing project.

Target audience

Graduate students, post-docs and PI's.

Biology Day

Monday 24 October 2016

Earlham Institute will be taking part in Norwich Science Festival’s Biology Day. Come and investigate genetic structure and base pairs with our scientists by taking part in our Message in a Bracelet Activity. Can you guess what the message is?

Solving Problems with Science - presented by Norwich Research Park

Saturday 29 October 2016

Earlham Institute will be taking part in Norwich Science Festival’s Solving Problems with Science Day. Come and have a go at conducting your own fruit DNA Extraction and chat to our scientists about the type of work they do at the institute.

On Tuesday 8th November, the Earlham Institute (formerly the Genome Analysis Centre) will offer a seminar in the Genome Building on Norwich Research Park.

Panel Discussion

6:30 - 7:40 pm

Tackling agriculture challenges with Next Generation Sequencing and High Performance Computing Technologies

Headed by experts at the Earlham Institute, a panel discussion will introduce key research themes and illustrate how next generation sequencing technologies and high performance computing is applied to answer biological questions.

This session will aim to highlight the challenges faced by breeders, farmers and wider industry and how Earlham Institute’s open-source tools, databases and innovative in-field technologies are being developed to support them. Open discussion is encouraged through questions from the audience relating to the panel discussion and any issues that it raises.

Speakers:

Wilfried Haerty Group Leader

Kirsten McLay Platforms & Pipelines Operational Manager                          

Timothy Stitt Head of Scientific Computing

Ji Zhou Phenomics Project Leader

Interactive Workshop - Three Horizons

8:30 - 9:30 pm

Led by experts at the Earlham Institute, these workshops will promote the sharing of key challenges and potential solutions including: new technology and accessibility, data storage and analysis, fast response to pests and disease, health of farm animals and the application of next-generation sequencing to crop breeding. Through discussion of current problems and existing innovations, the groups will identify future goals and construct a ‘route map’ of how we can get there.